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Important Patient Information
VARENICLINE - ORAL (var-e-NI-kleen) COMMON BRAND NAME(S): ChantixIMPORTANT NOTE: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your health care professional. Always seek the advice of your health care professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your health care professional. This information does not contain any assurances that this product is safe, effective, or appropriate for you.
USES: This medication is used in combination with a stop-smoking program (e.g., education materials, support group, counseling) to help you quit smoking. Varenicline works by blocking nicotine's actions in the brain. Quitting smoking decreases your risk of heart and lung disease, as well as cancer.
HOW TO USE: Follow your doctor's directions carefully. Before beginning treatment with this drug, set a date to quit smoking. Begin taking varenicline 1 week before the quit date as follows unless directed otherwise by your doctor. When you first start taking this medication, take one 0.5-milligram tablet once a day for 3 days, then increase to one 0.5-milligram tablet twice a day for 4 days. The dose is slowly increased to lessen the chance of side effects (e.g., nausea, unusual dreams). During this first week, it is okay to smoke. Stop smoking on the quit date and begin taking one 1-milligram tablet twice a day for the rest of the 12-week treatment period. If this medication comes in a dosing package, carefully follow the directions on the dosing package. There are two types of dosing packs, a starting pack and a continuing pack, each containing different strengths of this medication. Take this medication by mouth after food and with a full glass of water. Dosage is based on your medical condition and response to therapy. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Inform your doctor if you continue to smoke after a few weeks of treatment. If you are successful and cigarette-free after 12 weeks of treatment, your doctor may recommend another 12 weeks of treatment with varenicline.
SIDE EFFECTS: Nausea, headache, vomiting, gas, constipation, trouble sleeping, unusual dreams, or changes in taste may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking varenicline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease (especially kidney dialysis). Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for nausea and other side effects while using this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because this drug may have undesirable effects on a nursing infant, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: nicotine replacement therapy (e.g., patch, gum, nasal spray). Smoking can affect the way your body removes certain drugs. When you stop smoking, your doses of these drugs may need to be adjusted by your doctor. Tell your doctor if you take any of the following medications. Some of the drugs that smoking may affect, among others, are: "blood thinners" (e.g., warfarin), insulin, theophylline.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents should call the US National Poison Hotline at 1-800-222-1222. Canada residents should call a provincial poison control center.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.